DSpace About DSpace Software DSpace

Repository KhNMU >
Кафедри >
Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки >
Наукові роботи молодих вчених. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки >

Please use this identifier to cite or link to this item: http://repo.knmu.edu.ua/handle/123456789/3555

Название: Vascular Remodeling And Arterial Stiffness In Hypertensive Patients With Obesity
Другие названия: Ремоделювання судин та артеріальна жорсткість у хворих на гіпертонічну хворобу з ожирінням
Ремоделирование миокарда и артериальная жёсткость у больных гипертонической болезнью с ожирением
Авторы: Honchar, Oleksii
Гончарь, Олексій Володимирович
Гончарь, Алексей Владимирович
Ключевые слова: hypertension
vascular remodeling
arterial stiffness
гіпертонічна хвороба
артеріальна гіпертензія
ремоделювання судин
пружно-еластичні властивості
гипертоническая болезнь
артериальная гипертензия
ремоделирование сосудов
упруго-эластические свойства
Issue Date: 2013
Библиографическое описание: Honchar, Oleksii. Vascular Remodeling And Arterial Stiffness In Hypertensive Patients With Obesity / Honchar, Oleksii // 6th International Scientific Interdisciplinary Conference (ISIC) for medical students and young doctors, Kharkiv, 16-17 May 2013 : Abstract book / KhNMU. – Kharkiv, 2013. – Р. 51-52.
Аннотация: Objective. To investigate the peculiarities of common carotid artery (CCA) remodeling and stiffness in hypertensive patients with obesity. Design and method. 82 hypertensive patients with preserved LV systolic function had been observed, including 26 non-obese patients (1st group), 30 patients with the 1st degree of obesity (2nd), and 26 with the 2nd-3rd degree of obesity (3rd). An ultrasound examination of CCA gave a possibility to classify the patients according to its geometry (A.V. Agafonov, 2007) and to calculate the CCA stiffness indices. The statistical analysis was conducted using Mann-Whitney and Pearson χ2 methods. Results. Normal CCA geometry in the 1st gr. was observed in 17 (65,4%) patients, 2nd - 17 (56,7%), 3rd - 15 (57,7%), р=0,035; concentric remodeling – in 4 (15,4%), 4 (13,3%) and 2 (7,7%) accordingly; concentric hypertrophy (CH) – in 4 (15,4%), 6 (20,0%) and 7 (26,9%, р=0,035 within group); eccentric hypertrophy (EH) – in 1 (3,8%), 3 (10,0%) and 2 (7,7%) patients. Intima-media (IMT) thickening was observed in 42,3% non-obese and 64,3% obese patients, р=0,032. Petersen (Pet), Young (Einc) elastic modules as well as pulse wave velocity (PWV) were increasing with the degree of obesity, p>0,05. Cluster analysis by meanings of Pet and Einc gave a possibility to distribute the patients to 3 clusters, p=0,086. Body weight in the 1st cluster was 86,6 (73,5; 97,5) kg, 2nd – 91,7 (80,0; 100,9), 3rd – 98,3 (79,0; 108,8), p=0,059; body mass index (BMI) – 31,0 (28,8; 35,2) kg/m2, 31,3 (28,1; 37,3) and 32,1 (28,9; 35,8), p>0,05; waist circumference – 106,5 (99,5;112,5) cm, 112,5 (100,3; 117,5) and 115,5 (103,0; 119,5), p=0,071; W/H ratio – 0,94 (0,91; 1,01), 0,96 (0,91; 0,98) and 0,97 (0,94; 1,04), p=0,048. The age, levels systolic and pulse BP also had the highest values in the patients with higher stiffness indices, p<0,01. Conclusion. Hypertensive patients with obesity were characterized by higher prevalence of CCA remodeling. Arterial stiffnes indices were associated with age, weight, waist circumference, W/H ratio, SPB and PBP, but not BMI of patients.
URI: http://repo.knmu.edu.ua/handle/123456789/3555
Appears in Collections:Наукові роботи молодих вчених. Кафедра пропедевтики внутрішньої медицини № 1, основ біоетики та біобезпеки

Files in This Item:

File Description SizeFormat
Гончарь О.В._2013_005.pdfТези конференції90,91 kBAdobe PDFView/Open
Гончарь О.В._2013_005.docПрепринт34,5 kBMicrosoft WordView/Open

This item is protected by original copyright

View Statistics

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback